Authors
Lena Collienne, Frederick A Matsen Iv
Published in
Bulletin of mathematical biology. Volume 88. Issue 11. Oct 09, 2026. Epub Oct 09, 2026.
Abstract
Tree rearrangements such as Nearest Neighbor Interchange (NNI) and Subtree Prune and Regraft (SPR) are commonly used to explore phylogenetic treespace. Computing distances based on them, however, is often intractable, so the efficiently computable Robinson-Foulds (RF) distance is used in practice. We investigate how the RF distance behaves along paths in the NNI and SPR graphs, where trees are nodes and edges represent single rearrangements. We show that any two trees are connected by a path along which the RF distance to the target decreases monotonically in the NNI graph and strictly in the SPR graph; we also show that a strictly decreasing NNI path does not always exist.
PMID:
42853487
Bibliographic data and abstract were imported from PubMed on 10 Oct 2026.
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