Authors
Yu Pu, Jianping Jiang, Wenhui Chen, Yuzhi Wang, Yunjie Zhang, Zheng Huang
Published in
Photodiagnosis and photodynamic therapy. Pages 105677. Oct 09, 2026. Epub Oct 09, 2026.
Abstract
Since Hemoporfin for Injection was approved for marketing in China in 2016, Hemoporfin-mediated photodynamic therapy (Hemoporfin PDT) has become an important option for the treatment of port wine stain (PWS) birthmarks in China. The active ingredient of Hemoporfin is hematoporphyrin monomethyl ether (HMME) which is a second-generation porphyrin type photosensitizer preparation with a well-defined chemical structure. This article is the second part of a series focused on the research progress of Hemoporfin and aims to systematically review the clinical applications of Hemoporfin PDT in the treatment of PWS birthmarks. The article will highlight key clinical trial evidence, influential factors affecting efficacy and the safety profiles. Clinical studies related to pediatric patients will also be discussed. Available real-world evidence indicates that Hemoporfin PDT is an effective and safe treatment option for naïve and pulsed dye laser (PDL)-resistant PWS of children and adults.
PMID:
42855026
Bibliographic data and abstract were imported from PubMed on 10 Oct 2026.
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