Guidelines for the prevention and treatment of stress ulcers in critically ill patients (2026).

Authors

Guideline Working Group of the Chinese Society of Critical Care Medicine, Yan Kang, Xiangdong Guan, Dechang Chen

Published in

Journal of intensive medicine. Volume 6. Issue 6. Pages 537-556. Epub Sep 28, 2026.

Abstract

Stress ulcers is a common complication in critically ill patients, associated with increased mortality risk and prolonged intensive care unit stay. In recent years, several large-scale clinical studies on risk factors, prevention, and treatment of stress ulcers have provided new evidence for guideline development. Moreover, the lack of standardized protocols for the prevention and treatment of stress ulcers in clinical practice underscores the urgent need for authoritative guidelines to address inconsistent in management strategies. Accordingly, the Chinese Society of Critical Care Medicine established a multidisciplinary expert panel to develop the "Guidelines for the Prevention and Treatment of Stress Ulcers in Critically Ill Patients(2026)". Following the Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology, the guideline formulation process involved proposing clinical questions, literature retrieval and screening, meta-analysis and evidence synthesis, initial formation of recommendation items, panel reviews, three rounds of remote meetings, four rounds of face-to-face meetings, manuscript revisions, and final approval by the Standing Committee of the Society. The guidelines were finalized in the form of 23 evidence-based recommendations. These guidelines cover key aspects of stress ulcer management, including risk factors, prevention, treatment, and adverse effects of acid-suppressive drugs. The aim is to provide evidence-based guidance for healthcare professionals and promote standardized clinical management of stress ulcers in adults.

PMID:
42859621
Bibliographic data and abstract were imported from PubMed on 11 Oct 2026.

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