Preoperative Sedation via Cecostomy Tube in an Autistic Adolescent: A Case Report.

Authors

Ian M Drillings, Stephanie E Jones

Published in

A&A practice. Volume 20. Issue 10. Pages e02313. Oct 01, 2026. Epub Oct 14, 2026.

Abstract

Preoperative sedation of autistic children is frequently complicated by challenges in communication, sensory processing, and participation in medical care. We report a 40-kg, 13-year-old autistic boy with a preexisting cecostomy tube for chronic constipation, in whom previous oral and intramuscular sedation had failed due to agitation and physical aggression. Midazolam 10 mg (0.25 mg/kg) and ketamine 200 mg (5 mg/kg) were administered via cecostomy tube, producing sedation within 20 minutes. Dental rehabilitation under general anesthesia proceeded uneventfully. Cecal administration of sedatives may be a feasible option when conventional routes are poorly tolerated, although absorption, dosing, and reproducibility remain uncertain.

PMID:
42874046
Bibliographic data and abstract were imported from PubMed on 15 Oct 2026.

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