Authors
Déan van Tuil, Vera A Ottens, Kateryna Pirkovets, Berkay A Cakal, Giusi Pisano, Matthijs J V Scheltema, Daphne D D Rietbergen, Paolo Dell'Oglio, Elio Mazzone, Pim J van Leeuwen, Henk G van der Poel, Matthias N van Oosterom, Fijs W B van Leeuwen
Published in
npj digital surgery. Volume 1. Issue 1. Pages 26. Epub Oct 13, 2026.
Abstract
Translation of the drop-in gamma probe transformed radioguided robot-assisted prostate cancer (PCa) surgery. This study evaluated whether digitization of radiometric signals could allow conversion into more easier to interpret Augmented Reality radiation mapping (ARRM) displays. 20 PCa patients were included who underwent robot-assisted sentinel node (SN)- and prostate-specific membrane antigen (PSMA) radioguided resections (24 SNs, 16 PSMA-avid nodes and 1 PSMA-avid primary tumor). Radiometric probe counts/s (dimensionless) synchronized with positional probe data allowed the retrospective creation of dynamic ARRM overlays in two dimensions. Artificial intelligence was used to segment out, and automatically track, surgical instruments and dynamically de-occlude the ARRM displays accordingly. Retrospective scoring by end-users indicated a 72.5% preference for the ARRM displays compared to the currently available radiometric display (bipolar scale; median ≥2; p < 0.001). Thus, indicating that video-feed embedded ARRM visualizations provide a digital means to further advance the surgeon's perception of intraoperative molecular imaging.
PMID:
42876663
Bibliographic data and abstract were imported from PubMed on 15 Oct 2026.
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