Barriers and Enablers to Capsule Sponge Screening Among People With Heartburn: A Community-Based Qualitative Study in the UK.

Authors

Ninian Schmeising-Barnes, Emma Lidington, Elisavet Moschopoulou, Daksha Trivedi, Jo Waller

Published in

Health expectations : an international journal of public participation in health care and health policy. Volume 29. Issue 5. Pages e70919.

Abstract

Non-endoscopic capsule sponge devices are a promising new technology. They could potentially improve oesophageal cancer outcomes by detecting and monitoring Barrett's oesophagus and identifying dysplasia early to allow timely treatment. Trials assessing their clinical utility are underway.
This study sought to understand potential barriers and enablers to capsule sponge screening among people with heartburn.
Forty semi-structured interviews were conducted between October 2024 and April 2025 with men aged 55-79 and women aged 65-79 taking regular reflux medication. Participants were purposively sampled. Transcripts were analysed using Thematic Framework Analysis.
Participants were generally enthusiastic about the test, but not all felt willing or able to take part. Key factors influencing their attitudes are described in three overarching themes. First, participants described how they navigate reflux-related care and negotiate this with healthcare professionals. They considered how capsule sponge screening would fit into this collaborative model. Second, participants showed an aversion to uncertainty, noting that capsule sponge screening could both create and reduce uncertainty about their health. Third, participants' understanding of their candidacy varied based on risk perceptions, self-efficacy and views about acting on test results. Some expressed a sense of being less 'worthy' candidates than others.
Overall, the capsule sponge test screening appealed to many due to its quick, simple and minimally invasive approach. Nevertheless, concerns about responsibility for reflux care, candidacy and uncertainty will likely shape attitudes and intention towards the test and should be key considerations if this test is implemented.
Three individuals with lived experience of reflux, Barrett's oesophagus and oesophageal cancer were involved in the design of this study and associated materials.

PMID:
42878222
Bibliographic data and abstract were imported from PubMed on 16 Oct 2026.

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