Community-Acquired Klebsiella pneumoniae Meningitis With Liver Abscess and Neurological Sequelae in an Immunocompetent Adult: A Case Report.

Authors

Ghamdan Alsadeh, Sheema T Parakkal, Leyla K Bereka, Ahmed S Rahal

Published in

Cureus. Volume 18. Issue 9. Pages e116236. Epub Sep 14, 2026.

Abstract

Klebsiella pneumoniae meningitis (KPM) is a rare but severe form of community-acquired bacterial meningitis that is often associated with high mortality and neurological sequelae. We report a 46-year-old previously healthy male who presented with acute altered mental status and high-grade fever. Cerebrospinal fluid analysis was consistent with bacterial meningitis, and cultures from the cerebrospinal fluid and blood showed Klebsiella pneumoniae (K. pneumoniae) growth. The clinical course of the patient was complicated with seizures and acute right-sided hemiplegia. Persistent fever (despite appropriate antimicrobial therapy) prompted further evaluation, which revealed a hepatic abscess. Percutaneous abscess drainage resulted in rapid clinical improvement and notable neurological recovery. This case highlights the importance of early recognition of K. pneumoniae as a potential cause of community-acquired meningitis and the need to actively search for an underlying primary source, particularly a liver abscess, when the clinical response to antibiotics is suboptimal.

PMID:
42877895
Bibliographic data and abstract were imported from PubMed on 16 Oct 2026.

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