Authors
Zujing Wang, Wei Shen, Yu Ma, Ping Yu
Published in
Journal of visualized experiments : JoVE. Issue 236. Oct 16, 2026. Epub Oct 16, 2026.
Abstract
Patients with advanced cancer are particularly vulnerable to pressure injury (PI) because of immobility, symptom-related positioning constraints, moisture exposure, nutritional compromise, and progressive physiological deterioration. PIs can increase symptom burden and nursing complexity and substantially impair quality of life. This narrative review synthesizes evidence on PI risk assessment tools, risk factors, and preventive strategies for adults with advanced cancer. Evidence was drawn from oncology-specific validation and observational studies, palliative care literature, international clinical guidelines, and studies involving broader high-risk populations, with the directness and certainty of evidence distinguished for major recommendations. Oncology-specific evidence supports selected risk factors and assessment approaches, whereas much of the evidence for preventive interventions is extrapolated from non-oncology populations. Pressure-redistribution support surfaces, individualized repositioning, selective preventive dressings, nutritional care, and symptom management should therefore be tailored to PI risk, intervention burden, prognosis, patient preferences, and goals of care. To integrate these considerations, we propose a comfort-prioritized, risk-stratified conceptual framework for advanced cancer care. The framework supports individualized decision-making across palliative and actively dying phases while emphasizing both PI-related and patient-centered outcomes, including comfort, pain, sleep disruption, and goal-concordant care.
PMID:
42891608
Bibliographic data and abstract were imported from PubMed on 18 Oct 2026.
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