Genomic Epidemiology and Antimicrobial Susceptibility of Human Brucellosis - Shenzhen City, Guangdong Province, China, 2005-2024.

Authors

Li Yuan, Cong Niu, Shiting Chen, Qiongcheng Chen, Shuang Wu, Wenkai Cui, Jianguang Cai, Xiaolu Shi

Published in

China CDC weekly. Volume 8. Issue 40. Pages 1242-1251. Oct 02, 2026.

Abstract

Brucellosis is a zoonotic disease historically concentrated in pastoral regions of China; however, an increasing number of cases have been reported in large urban centers in recent years.
Analysis of 191 human-derived Brucella isolates collected in Shenzhen between 2005 and 2024 showed that Brucella melitensis predominated and that Shenzhen isolates were interspersed with strains from multiple provinces, suggesting repeated introductions from other regions. Most cases occurred in working-age adults, and both imported cases and Shenzhen-resident cases without documented external exposure were identified.
These findings suggest that brucellosis control in highly urbanized settings should prioritize surveillance for imported infections, improved traceability and regulation of animal-derived food products, targeted protection of high-risk occupational groups, and continued genomic and antimicrobial susceptibility surveillance.

PMID:
42891138
Bibliographic data and abstract were imported from PubMed on 18 Oct 2026.

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