Authors
Akash Shukla, Xiaolong Qi, Necati Ormeci, Ajay Duseja, Shiv Sarin
Published in
Journal of clinical and experimental hepatology. Volume 17. Issue 1. Pages 103671. Epub Sep 08, 2026.
Abstract
Background: There have been recent proposals to replace non-cirrhotic portal fibrosis (NCPF), idiopathic portal hypertension (IPH), idiopathic non-cirrhotic portal hypertension, nodular regenerative hyperplasia, etc. with an all-encompassing term "porto-sinusoidal vascular disorder." However, the Asia-Pacific Association for Study of the Liver recommended continued use of the term NCPF/IPH. Methods: We sent this questionnaire-based online survey to capture the clinical perspectives of 300 specialized experts in the Asia-Pacific region with complete anonymisation. Results: The survey (n = 242 respondents) revealed overwhelming support for the continued use of the NCPF/IPH nomenclature, with 93.4% of experts favoring the term in daily practice. Furthermore, 80.1% endorsed liver histopathology as a fundamental diagnostic component, while 95.9% agreed that a lower-than-cirrhosis-range liver stiffness measurement obtained via transient elastography in the presence of portal hypertension is highly indicative of the condition.A total of 91% agreed with the APASL staging system. Conclusions: The results highlight a persistent regional consensus favoring a clinical, histological and portal hypertension-driven diagnostic and staging framework for NCPF. The survey reveals strong support for the continued use of the NCPF/IPH nomenclature.
PMID:
42893017
Bibliographic data and abstract were imported from PubMed on 18 Oct 2026.
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