Phase Image Display Settings for Paramagnetic Rim Lesion Detection in Multiple Sclerosis: A Practical Guide.

Authors

Akifumi Hagiwara, Yuki Sonoda, Yuji Tomizawa, Koji Shinoda, Isamu Takai, Yasunobu Hoshino, Junko Kikuta, Taku Hatano, Koji Kamagata

Published in

Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine. Volume 25. Issue 4.

Abstract

The 2024 revisions of the McDonald criteria incorporate the paramagnetic rim lesion (PRL) into the diagnostic framework of multiple sclerosis, and PRL evolution is increasingly recognized as a marker of disease progression. PRLs are detected on phase images of susceptibility-sensitive sequences, but their visibility depends critically on display settings. Current consensus recommendations provide detailed guidance on acquisition parameters yet do not address the phase-image window/level applied at the reading workstation; an inappropriate phase window can render rims invisible. We discuss practical tips for reliable PRL detection, including awareness of vendor-specific phase conventions, windowing to optimize conspicuity, and hands-on training, to support accurate and reproducible PRL assessment in routine clinical practice.

PMID:
42893879
Bibliographic data and abstract were imported from PubMed on 19 Oct 2026.

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