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Trends in cardiovascular disease and risk factors between 2004 and 2021: Findings from the U.S. Millennium Cohort Study.

Created on 19 Oct 2026

Authors

Claire A Kolaja, Anna Baccetti, Sheila F Castañeda, Erin L Richard, Felicia R Carey, Edward J Boyko, Rudolph P Rull, Millennium Cohort Study Team

Published in

Preventive medicine. Pages 108687. Oct 18, 2026. Epub Oct 18, 2026.

Abstract

Cardiovascular disease (CVD) is a leading cause of death in the United States (U.S.). Military veterans have notably high prevalences of CVD. The aim was to report the prevalence of self-reported CVD and risk factors among post-9/11 veterans from 2004 to 2021.
The U.S. Millennium Cohort Study prospectively follows service members and veterans. Eligible participants enrolled in 2001, separated from the military by 2021, and provided CVD information post-separation. Data from cross-sectional snapshots were used to examine unadjusted and standardized prevalences of CVD and risk factors. Linear trends in prevalence tested for significant changes.
Among 43,769 participants (average baseline age 37.2) between 2004 and 2006 and 2019-2021, results show current smoking decreased from 23.7 to 8.2 per 100. Prevalence estimates for all other examined factors increased; obesity from 22.2 to 47.7 per 100, hypertension from 9.0 to 23.5 per 100, diabetes from 1.6 to 7.0 per 100. CVD outcomes were less common and increased from <0.8 to <3.0 per 100.
Among a population of post-9/11 veterans, most CVD factors increased between 2004 and 2021. Treatment and intervention programs targeted toward veterans transitioning to civilian life should consider weight management and healthy lifestyle factors related to CVD prevention.

PMID:
42893733
Bibliographic data and abstract were imported from PubMed on 19 Oct 2026.

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