[Tissue resident memory cells in psoriasis].

Authors

Nathasja Dorf Tams, Lasse Hougaard Rishøj, Kasper Fjellhaugen Hjuler

Published in

Ugeskrift for laeger. Volume 188. Issue 40. Sep 28, 2026. Epub Sep 28, 2026.

Abstract

Tissue resident memory cells (Trm-cells) function as both benign and pathogenic memory cells. Benign Trm-cells play an important role in adaptive immunity by protecting against external pathogens, whereas pathogenic Trm-cells can induce relapses in several chronic skin diseases, including psoriasis. Early and intensive treatment with biologic therapy can lead to effective, long-term disease control by limiting local memory formation in the skin. However, this review finds it important not to compromise the beneficial role of Trm-cells in adaptive immunity when pursuing long-term treatment strategies.

PMID:
42894954
Bibliographic data and abstract were imported from PubMed on 19 Oct 2026.

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