All-in-One Augmented Reality Guided Head and Neck Tumor Resection.

Authors

Yue Yang, Matthieu Chabanas, Carrie Reale, Annie Benson, Jason Slagle, Matthew Weinger, Michael Topf, Jie Ying Wu

Published in

Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention. Volume 16893. Pages 23-31. Epub Sep 26, 2026.

Abstract

Positive margins are common in head and neck squamous cell carcinoma, yet intraoperative re-resection is often imprecise because margin locations are typically communicated verbally from pathology. We present an all-in-one augmented reality (AR) system that relocalizes positive margins from a resected specimen to the resection bed and visualizes them in situ using HoloLens 2 depth sensing and fully automated markerless surface registration. In a silicone phantom study with six medical trainees, markerless registration achieved target registration errors comparable to a marker-based baseline (median 1.8 mm vs. 1.7 mm; maximum < 4 mm). In a margin relocalization task, AR guidance reduced error from verbal guidance (median 14.2 mm) to a few millimeters (median 3.2 mm), with all AR localizations within 5mm error. These results support the feasibility of markerless AR margin guidance for more precise intraoperative re-resection.

PMID:
42894872
Bibliographic data and abstract were imported from PubMed on 19 Oct 2026.

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