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Invasive Infections Caused by Streptococcus pseudoporcinus: A Two-Case Series and Review of the Literature.

Created on 19 Oct 2026

Authors

Julio de Jesús Navarro-Yépez, Frida Ximena Macías-López, David Alejandro Trejo-Osornio, Juan Manuel Gomez-Vasquez, Gilberto Gutierrez-Garcia

Published in

Cureus. Volume 18. Issue 9. Pages e116454. Epub Sep 17, 2026.

Abstract

Streptococcus pseudoporcinus (S. pseudoporcinus) is a beta-hemolytic, Gram-positive, catalase-negative, nonmotile coccus that primarily colonizes the female genitourinary tract. Although it has historically been considered a colonizing organism, it has increasingly been associated with invasive infections. Its identification may be challenging because of its phenotypic similarity to other beta-hemolytic streptococci. We report two invasive infections caused by S. pseudoporcinus. The first occurred in a 59-year-old woman with cirrhosis who developed spontaneous bacterial peritonitis in the setting of chylous ascites. The second occurred in a 50-year-old woman who presented with pneumonia, hypoxemic respiratory failure, and a complicated parapneumonic effusion. S. pseudoporcinus was recovered from ascitic fluid and pleural fluid, respectively, and was identified using the VITEK 2 Compact (bioMérieux, Marcy-l'Étoile, France) system. Both patients received antimicrobial therapy and experienced favorable clinical outcomes without documented recurrence during follow-up. These cases expand the recognized clinical spectrum of invasive S. pseudoporcinus infection and emphasize the importance of accurate species-level identification of beta-hemolytic streptococci recovered from normally sterile sites.

PMID:
42894538
Bibliographic data and abstract were imported from PubMed on 19 Oct 2026.

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