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Preliminary clinical changes during use of a personalized video-based mobile intervention for community-dwelling individuals with severe mental illness: An exploratory randomized crossover trial.

Created on 19 Oct 2026

Authors

Yong Hyuk Cho, Anna You, Sooin Jeong, Ga Eun Kim, Sun Hwa Hong, Sang Joon Son, Bumhee Park, Joung Hwan Back, Chang Hyung Hong

Published in

Internet interventions. Volume 46. Pages 101004. Epub Oct 08, 2026.

Abstract

Severe mental illness (SMI) often limits participation in traditional therapy due to motivational and cognitive deficits. We examined short-term clinical changes during use of a personalized video-based mobile app (MARO)-providing psychoeducation, emotion regulation, cognitive restructuring, and behavioral activation-in community-dwelling individuals with SMI and explored whether the timing of minimal human coaching was associated with these outcomes. This 8-week exploratory randomized crossover trial compared an Immediate-Coaching group (app + coaching → app only) and a Delayed-Coaching group (app only → app + coaching); both groups used MARO throughout the study. Among 40 randomized participants, 27 completed all assessments. Depression (Patient Health Questionnaire-9), anxiety (Generalized Anxiety Disorder-7), and positive automatic thoughts (Automatic Thoughts Questionnaire-Positive) were assessed at baseline and after 4 and 8 weeks. Both groups showed decreases in PHQ-9 and GAD-7 scores over the 8-week intervention period, while ATQ-P scores increased. Overall PHQ-9 scores were lower and ATQ-P scores were higher in the Immediate-Coaching group than in the Delayed-Coaching group. These preliminary findings support further evaluation in larger, adequately powered controlled studies of personalized video-based mobile interventions as a potentially scalable digital-human approach to community-based care for individuals with severe mental illness. Trial Registration: CRIS, KCT0011492.

PMID:
42894670
Bibliographic data and abstract were imported from PubMed on 19 Oct 2026.

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