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When the Tumor Disappears, Must the Larynx Follow?

Created on 19 Oct 2026

Authors

Achraf A Shamseddine, Nadeem Riaz

Published in

Clinical cancer research : an official journal of the American Association for Cancer Research. Oct 19, 2026. Epub Oct 19, 2026.

Abstract

REMATCH, a single-institution phase II study, evaluated reduced-volume surgery in patients with locally advanced head and neck cancer responding to neoadjuvant immunochemotherapy. Two-year disease-free survival was 90%, with universal laryngeal preservation. The trial advances organ preservation by reducing the extent and intensity of local therapy rather than substituting modalities.

PMID:
42895477
Bibliographic data and abstract were imported from PubMed on 19 Oct 2026.

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