Fingerprinting the polycystic kidney: radiomics of the noncystic parenchyma for earlier ADPKD detection.

Authors

Timothy L Kline

Published in

Kidney international. Volume 110. Issue 5. Pages 1100-1101.

Abstract

Autosomal dominant polycystic kidney disease risk stratification relies on total kidney volume, a validated marker of cyst burden and progression. Kremer et al.'s pilot study used rapid breath-hold magnetic resonance fingerprinting with radiomics to evaluate noncystic renal parenchyma in children and young adults. Quantitative T1/T2 texture features distinguished autosomal dominant polycystic kidney disease from controls independently of total kidney volume, cyst fraction, age, or body size, suggesting early tissue changes. Small, cross-sectional, unmatched data require longitudinal validation of reproducibility, prognostic value, and clinical utility.

PMID:
42901686
Bibliographic data and abstract were imported from PubMed on 21 Oct 2026.

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