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Preoperative Factors Associated With Pulmonary Embolism Following Primary Total Hip Arthroplasty: An ACS-NSQIP Analysis of 2017-2021 Data.

Created on 23 Oct 2026

Authors

Niki R Patel, Pranay Gadikota, Thor S Stead, Omar Viswanath, Latha Ganti

Published in

Orthopedic reviews. Volume 18. Pages 172452. Epub Oct 19, 2026.

Abstract

This study examined preoperative factors associated with 30-day pulmonary embolism (PE) after primary total hip arthroplasty.
ACS-NSQIP records from 2017-2021 with CPT code 27130 were analyzed. Complete cases were included using cleaned body mass index (BMI), age, sex, steroid use, and disseminated cancer. These five variables were entered jointly into logistic regression.
Among 196,495 complete cases, 484 (0.246%) had PE. Adjusted odds ratios were 6.44 for disseminated cancer, 1.69 for steroid use, 1.23 for female sex, 1.041 per year of age, and 1.031 per kg/m² of BMI (all P < .05). Apparent AUC was 0.647 (95% CI, 0.622-0.672). The Hosmer-Lemeshow test indicated lack of fit (P = .012).
Five preoperative characteristics were associated with PE. Discrimination was modest, calibration limitations were present, and validation is required before clinical use.

PMID:
42908541
Bibliographic data and abstract were imported from PubMed on 23 Oct 2026.

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