Characterization of Diabetic Retinopathy in Trimesters of Pregnancy.

Authors

Kanika Seth, Neil A Rana, Jason M Singer, Rishi P Singh, Katherine E Talcott

Published in

Journal of vitreoretinal diseases. Pages 24741264261496246. Oct 20, 2026. Epub Oct 20, 2026.

Abstract

To evaluate the relationship between trimester of pregnancy and stage of diabetic retinopathy (DR) in a cohort of women with diabetes.
In this single-center, retrospective cohort study, data were collected from adult women with diabetes who experienced a pregnancy at 5 timepoints: prepregnancy, each trimester, and postpregnancy. Progression, manifestation, and improvement of DR were tracked via logistic regression.
A total of 158 patients were analyzed. Among them, 13 (8.2%) showed progression to worse stage of DR during pregnancy, of whom 6.9%, 5.0%, and 14.3% had progression within the prepregnancy/first trimester, second trimester, and third trimester brackets, respectively, and 10.0% progressed postpregnancy; differences between the trimesters regarding incidence of DR progression were nonsignificant (P = .42). Of patients with no retinopathy at baseline, 4.62%, 7.69%, and 5.88% developed DR in each of the 3 trimesters, respectively, and 6.45% developed DR postpregnancy; differences in rates of DR manifestation were nonsignificant (P = .97).
Pregnancy stage was not associated with risk of DR manifestation or progression in this cohort.

PMID:
42909157
Bibliographic data and abstract were imported from PubMed on 23 Oct 2026.

Read full publication at:
Please sign in to see all details.

Stats

1-terrible, 9-excellent. How would you rate this publication? Sign in in to submit your rating.

Post a comment

You need to be signed in to post comments. You can sign in here.

Comments

There are no comments yet.