18F-fluorodeoxyglucose Positron Emission Tomography with Computed Tomography in Pediatric Non-oncological Conditions: A Comprehensive Review.

Authors

Chandrasekaran Ganapathy, Priyanka Gb, Raman Toshniwal, Rakesh Kumar

Published in

PET clinics. Oct 23, 2026. Epub Oct 23, 2026.

Abstract

This article examines the expanding role of 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography with computed tomography (PET/CT) in pediatric non-oncological conditions, moving beyond its established oncologic use. It outlines radiation dosimetry principles unique to children-emphasizing the As Low as Reasonably Achievable principle, reduced tracer activity, and low-dose CT protocols-given their heightened radiosensitivity. In pediatric neurology, FDG PET/CT aids evaluation of drug-refractory epilepsy (temporal and extratemporal foci) and neuronal migration/proliferation anomalies like focal cortical dysplasia (FCD), polymicrogyria, and hemimegalencephaly.

PMID:
42919721
Bibliographic data and abstract were imported from PubMed on 24 Oct 2026.

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