Clinicodemographic and epidemiological factors associated with dengue severity and outcomes among hospitalized patients in Navi Mumbai, India: A retrospective study.

Authors

Swati A Bhosle, Dhaval M Throat, Sonal G Somwanshi, Suparna B Khera

Published in

Journal of vector borne diseases. Oct 22, 2026. Epub Oct 22, 2026.

Abstract

Dengue is a major public health concern in developing countries like India, with rising incidence in urban and peri-urban areas. Disease severity varies from mild illness to severe dengue with multiorgan dysfunction and mortality. To analyse clinicodemographic characteristics and predisposing risk factors associated with dengue severity and outcomes, and to assess duration of hospitalization across different severity categories.
A retrospective hospital-based study was conducted among 302 laboratory-confirmed dengue patients admitted to a tertiary care hospital in Navi Mumbai, Maharashtra, India, between July 2023 and December 2024. Dengue severity was classified as mild, moderate and severe as per National Guidelines for Clinical Management of Dengue Fever (2023).
Majority were adults (75.2%) with male predominance (60.9%). Most cases were reported during the post-monsoon season. Moderate dengue constituted (64.9%) of cases, while (11.9%) being severe. Elderly age (OR = 4.35; 95% CI: 1.62-11.64) and presence of comorbidities (OR = 2.79; 95% CI: 1.25-6.24) were significantly associated with severe dengue (p < 0.05). Mean duration of hospitalization increased significantly with severity (mild: 4.0 days; moderate: 4.6 days; severe: 5.8 days; p < 0.001). Six deaths (2.0%) occurred among the 302 patients, all of which (16.7%) occurred in the severe dengue group.
Elderly age and comorbidities were significantly associated with severe dengue. Early identification and close monitoring of high-risk groups, along with timely supportive management and targeted preventive measures, are essential to reduce morbidity and mortality.

PMID:
42925571
Bibliographic data and abstract were imported from PubMed on 25 Oct 2026.

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