Sentinel lymph node-guided modification of postoperative radiotherapy in oral tongue squamous cell carcinoma: a retrospective dosimetric and NTCP modelling study.

Authors

Einar Björgvinsson, Aeneas Kolev, Eva Onjukka, Mattias Hedman, Åsa Carlsson Tedgren, Lars Södergren, Signe Friesland, Gregori Margolin, Lars-Olaf Cardell, Michael Gubanski

Published in

Clinical and translational radiation oncology. Volume 62. Pages 101306. Epub Oct 08, 2026.

Abstract

•SLNB identified lymphatic drainage beyond standard elective volumes in nearly half of OTSCC patients.•SLNB may guide individualized postoperative radiotherapy, including omission of contralateral neck irradiation in selected patients.•Adapted plans significantly reduced estimated NTCPs for xerostomia and dysphagia.•SLNB may support individualized de-escalation and optimization of elective neck irradiation in OTSCC.

PMID:
42927216
Bibliographic data and abstract were imported from PubMed on 25 Oct 2026.

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