Authors
Asmae Bali, Kaouthar Khater, Fadoua Jebrouni, Hind Chibani, Ouissam Al Jarroudi, Sami Aziz Brahmi, Said Afqir
Published in
Cureus. Volume 18. Issue 9. Pages e116888. Epub Sep 25, 2026.
Abstract
Primary cervical endometrial stromal sarcoma (ESS) is a challenging mesenchymal neoplasm that may present with non-specific clinical manifestations and advanced local disease at diagnosis. We report the case of a 50-year-old diabetic woman presenting with metrorrhagia and pelvic pain. Clinical examination revealed a large ulcerative cervical mass infiltrating the vaginal walls. Histopathology with immunohistochemistry supported the diagnosis of ESS. Imaging demonstrated extensive loco-regional invasion of the bladder, lower vagina, and rectal wall, consistent with FIGO stage IVA disease. The patient was treated with systemic chemotherapy (carboplatin-paclitaxel). This case highlights the diagnostic challenges of cervical ESS, the importance of histopathological and immunohistochemical evaluation, and the therapeutic considerations in locally advanced disease.
PMID:
42928860
Bibliographic data and abstract were imported from PubMed on 26 Oct 2026.
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