Genetic Testing in Irritable Bowel Syndrome.

Authors

Nielson Weng, Braden Kuo, Kyle Staller

Published in

Gastroenterology clinics of North America. Volume 55. Issue 4. Pages 741-758. Epub Sep 09, 2026.

Abstract

Irritable bowel syndrome (IBS) is a complex genetic disorder characterized by polygenic susceptibility with substantial environmental modulation. While many candidate gene studies and large genome-wide association studies have identified loci associated with IBS susceptibility, the role of genetic testing for IBS in clinical practice is uncertain. Instead, emergent areas such as pharmacogenetics and nutrigenetics may offer more immediate clinical applications by guiding medication or dietary interventions.

PMID:
42933944
Bibliographic data and abstract were imported from PubMed on 27 Oct 2026.

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