From Controversy to Clarity: The New Landscape of Pediatric Autoimmune Hepatitis Care.

Authors

Alyssa R Goldberg, Silvia Nastasio, Cara L Mack

Published in

Clinics in liver disease. Volume 30. Issue 4. Pages 925-941. Epub Sep 01, 2026.

Abstract

Over the past decade, there have been advancements in our knowledge of the pathogenesis of autoimmune hepatitis (AIH), resulting in diagnostic and prognostic biomarker discoveries and an expansion of treatment options. This article cites recent literature to aid clinicians in the understanding and awareness of diagnostic and treatment pitfalls and strategies. An overview of the current understanding of the immunopathogenesis of AIH, the diagnostic strategies to effectively exclude other chronic liver diseases, the evidence for emerging diagnostic and therapeutic biomarkers, and the management strategies for typical and difficult to treat cases is provided.

PMID:
42946525
Bibliographic data and abstract were imported from PubMed on 28 Oct 2026.

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