Authors
Meysam Fathi-Choghadeh, Harrison S Fellheimer, Matthew C Culkin, Lasya Sethi, Bryan A Hozack, Pedro K Beredjiklian
Published in
Hand (New York, N.Y.). Pages 15589447261496361. Oct 28, 2026. Epub Oct 28, 2026.
Abstract
While an association between carpal tunnel release (CTR) and subsequent trigger finger (TF) has been reported, existing studies have widely varied and often limited sample sizes and follow-ups. This study aimed to determine the risk of new-onset TF following CTR using a large national database.
A retrospective cohort study was conducted using the TriNetX US Collaborative Network. Patients with a diagnosis of carpal tunnel syndrome were grouped into 2 propensity score-matched cohorts: those who underwent CTR (n = 42 331) and those who did not (n = 42 331). The primary outcome was a new diagnosis of TF at various time intervals up to 5 years. Odds ratios (ORs) and Cox proportional hazards models were used to compare risk between cohorts.
During the 5-year follow-up, patients who underwent CTR had a significantly higher incidence of TF compared with the non-surgical cohort (9.2% vs 3.1%; hazard ratio, 2.56; 95% CI, 2.40-2.72; P < .0001). The risk was most pronounced within the first 6 months postoperatively (CTR 1.9% vs non-CTR 0.4%; OR, 5.38; 95% CI, 4.53-6.39). This elevated risk remained significant at 1 year (OR, 4.41) and persisted at 5 years (OR, 3.18).
This large-scale analysis demonstrates a significant and sustained association between CTR and the subsequent development of TF, with patients being over 5 times more likely to develop TF in the first 6 months after surgery. These findings underscore the importance of preoperative thorough patient counseling and postoperative awareness for early diagnosis of TF.
PMID:
42947657
Bibliographic data and abstract were imported from PubMed on 28 Oct 2026.
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