Emerging Technologies for the Discovery and Characterization of Microbial Natural Products.

Authors

Simon Sieber

Published in

Chimia. Volume 80. Issue 10. Pages 664-670. Oct 28, 2026. Epub Oct 28, 2026.

Abstract

The discovery of natural products has changed dramatically in recent years, and new technologies have been developed continuously to improve this process, including the integration of artificial intelligence tools. Herein, we summarize some emerging methodologies, including genome mining, activation of selected biosynthetic pathways, chemical probes, and mass spectrometry-based metabolomics. Selected examples are discussed in detail, highlighting and describing their discovery strategies.

PMID:
42949511
Bibliographic data and abstract were imported from PubMed on 28 Oct 2026.

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