Bimetallic synergy-induced Ce/Cu coordination polymer nanozyme with broad-temperature oxidase activity for smartphone-assisted antioxidant sensing.

Authors

Nan Gao, Xiaojun Liu, Qingshuang Liu, Zexin Wang, Xiaolei Zhang, Haozhang Li, Baolong Zhang, Dongjun Lv

Published in

Analytica chimica acta. Volume 1425. Pages 346294. Dec 01, 2026. Epub Sep 18, 2026.

Abstract

Total antioxidant capacity (TAC) reflects food quality and redox state, and a simple, sensitive assay is needed. We synthesized a bimetallic AMP-Ce/Cu coordination polymer by one-pot room-temperature coordination of Ce⁴⁺, Cu²⁺, and adenosine monophosphate (AMP). Electronic coupling between Ce and Cu gave the polymer oxidase-like activity, letting it activate dissolved O₂ directly; the bimetallic material reached ∼4-fold the activity of AMP-Ce⁴⁺ alone. Scavenger and electron paramagnetic resonance (EPR) assays showed superoxide radical as the dominant oxidant, with hydroxyl radical secondary. The sensor responded to AA linearly from 15 to 1750 nM and detected down to 4.5 nM. The oxidase-like activity retained >90% of its peak value across 0-55 °C. A paper-based strip delivered rapid, smartphone-assisted on-site readout. Applied to five tea varieties, the method separated their TAC levels. This work shows that lanthanide-transition-metal coordination polymer nanozymes can serve broad-temperature, on-site TAC detection.

PMID:
42951532
Bibliographic data and abstract were imported from PubMed on 29 Oct 2026.

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