Authors
Youping Zhou, Mingfeng Liu, Rui Yuan, Yu Ou, Xiaofeng Yang, Haojie Zhang, Yichun Yang, Binglan Zhang, Shan Li, Liang Deng
Published in
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver. Oct 29, 2026. Epub Oct 29, 2026.
Abstract
This study evaluated the clinical feasibility of precutting endoscopic band ligation-assisted resection (precutting EBLR) for the removal of small gastric submucosal tumors originating from the muscularis propria (gSMT-MP).
This was a single-center, open-label, parallel-group randomized controlled trial (ChiCTR2200065473). All endoscopic procedures were performed by two experienced endoscopists (>300 ESD cases each). From January 2023 to December 2024, consecutive patients with gSMT-MP ≤ 16 mm were enrolled and randomly assigned to precutting EBLR or ESD. The primary outcome was operation time, additional clinical indicators were also collected and analyzed.
The median operation time was 17.5 min (range: 12-50) for the precutting EBLR group and 30 min (range: 12-80) for the ESD group. The median operation costs were $564.05 (range: $301.97-$1236.42) and $849.29 (range: $491.95-$2121.25), respectively. R0 and en-bloc resection were achieved in all patients. No delayed perforations or tumor recurrences occurred during follow-up.
Precutting EBLR demonstrated advantages in operation time compared with ESD. It represents an efficient and safe endoscopic approach for treating gSMT-MPs ≤ 16 mm, and may be potentially applicable in non-academic or lower-volume centers, pending further validation.
PMID:
42957495
Bibliographic data and abstract were imported from PubMed on 30 Oct 2026.
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