Left Ventricular Noncompaction Cardiomyopathy and Thromboembolic Complications: A Case Report and Focused Review of the Literature.

Authors

Leonardo Alexis Almaguer Gongora, Stephanie Shimon, Luis E Remedios Carbonell, Grettel Gonzalez, Carlos Acosta-Batista, Juan C Velasquez

Published in

The Permanente journal. Pages 1-6. Oct 30, 2026. Epub Oct 30, 2026.

Abstract

Left ventricular noncompaction cardiomyopathy (LVNC) is a rare myocardial disorder characterized by prominent trabeculations and deep intertrabecular recesses. Thromboembolic complications represent a major source of morbidity and mortality, yet optimal risk stratification and anticoagulation strategies remain poorly defined. The authors have reported the case of a patient with previously undiagnosed LVNC who presented with rapidly progressive heart failure and developed acute, recurrent cardioembolic strokes. Cardiac imaging revealed extensive left ventricular trabeculations, a severely reduced ejection fraction, and bilateral atrial appendage thrombi. Despite systemic anticoagulation, the patient experienced rapid respiratory and hemodynamic decompensation resulting in death. LVNC is associated with a substantial chance of thromboembolic events, particularly in patients with ventricular dysfunction. This case highlighted the crucial importance of early recognition and the need for individualized anticoagulation strategies in patients at high risk.

PMID:
42958876
Bibliographic data and abstract were imported from PubMed on 30 Oct 2026.

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