Multi-Layered Regulation of Anthocyanin Biosynthesis: Emerging Mechanisms and Implications for Nutritional and Stress-Resilient Crops.

Authors

Mirza Muhammad Ahad Baig, Muhammad Ali Abid, Zhaoyi Liao, Tao Zhou, Hongzhe Wang, Qi Zhou, Yanyan Li, Ting Wen, Waqas Malik, Zhigang Meng, Yuan Wang, Sandui Guo, Minnan Qu, Chengzhen Liang

Published in

Plant communications. Pages 102165. Oct 30, 2026. Epub Oct 30, 2026.

Abstract

Anthocyanins are pivotal pigments in plants, imparting vivid coloration and providing substantial nutritional and ecological benefits. While classical reviews have largely focused on biosynthetic enzymes, emerging evidence highlights a multi-layered regulatory architecture that integrates transcriptional control, chromatin state, intracellular transport, hormonal signalling, and environmental cues. In this review, we integrate current knowledge of the MYB-bHLH-WD40 regulatory complex together with emerging mechanisms involving chromatin dynamics, DNA methylation, histone modifications, non-coding RNAs, protein modifications, nutrient signalling, and stress-responsive pathways that collectively fine-tune anthocyanin accumulation. Emphasizing future prospects, we propose anthocyanin-rich plants as strategic targets for enhancing nutritional quality, expanding market value, and improving stress resilience. By synthesizing current breakthroughs and future directions, this review elucidates a comprehensive and forward-looking framework that extends beyond conventional anthocyanin research, aiming to inspire innovative approaches in crop improvement and functional food development.

PMID:
42963918
Bibliographic data and abstract were imported from PubMed on 31 Oct 2026.

Read full publication at:
Please sign in to see all details.

Stats

1-terrible, 9-excellent. How would you rate this publication? Sign in in to submit your rating.

Post a comment

You need to be signed in to post comments. You can sign in here.

Comments

There are no comments yet.