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Antimicrobial susceptibility patterns of Group B Streptococcus isolates recovered from pregnant individuals in Greece.

Created on 02 Nov 2026

Authors

Karolina Akinosoglou, Maria Gavatha, Panayotis D Ziakas, Alexandros Psarris, Christina Vogiantzi, Eleni Polyzou, Aristotelis Tsiakalos

Published in

Diagnostic microbiology and infectious disease. Volume 117. Issue 1. Pages 117716. Oct 29, 2026. Epub Oct 29, 2026.

Abstract

Group B Streptococcus (GBS) remains an important pathogen in pregnancy and a major cause of neonatal morbidity and mortality. This study aimed to investigate the antimicrobial susceptibility profile of GBS isolates recovered from pregnant individuals in Greece. A retrospective observational study was conducted, including 89 non-duplicate GBS isolates recovered from vaginal and rectal swab specimens during routine antenatal screening at a maternity clinic in Athens, Greece, between 2021 and 2025. Bacterial identification was performed using the VITEK 2 automated system, and antimicrobial susceptibility testing was conducted by determining the minimum inhibitory concentration (MIC) according to the European Committee on Antimicrobial Susceptibility Testing (EUCAST) criteria. High resistance rates were observed for erythromycin and clindamycin, with 58.62% and 54.55% of tested isolates classified as resistant, respectively. Tetracycline showed the highest resistance rate (89.77%), while most isolates remained susceptible to benzylpenicillin (97.75%) and vancomycin (98.86%). Multidrug resistance was detected in 50% of isolates. These findings underscore the need for susceptibility-guided prophylaxis and ongoing surveillance of antimicrobial resistance in Greece.

PMID:
42967403
Bibliographic data and abstract were imported from PubMed on 02 Nov 2026.

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