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Reframing QSP: AI-Driven Multi-Modal Data as a New Measurement Layer.

Created on 03 Nov 2026

Authors

Jane Knöchel

Published in

CPT: pharmacometrics & systems pharmacology. Volume 15. Issue 11.

Abstract

Quantitative systems pharmacology (QSP) provides a mechanistic framework for integrating biological and pharmacological knowledge in drug development. Simultaneously, advances in artificial intelligence (AI), particularly in multi-modal data analysis, are transforming how biological information is derived. I argue that AI should not be viewed as a data integration tool, but as a new layer of quantitative measurement generation. This reframing positions QSP as a foundational model of biology, used here in a conceptual rather than technical sense, and AI as a source of quantitative inputs.

PMID:
42971924
Bibliographic data and abstract were imported from PubMed on 03 Nov 2026.

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