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Clot in Transit.

Created on 04 Nov 2026

Authors

Deepika Potarazu, Sana Sultana, Seth I Sokol, Carin Gonsalves, John M Moriarty

Published in

Clinics in chest medicine. Volume 47. Issue 4. Pages 809-819. Epub Sep 15, 2026.

Abstract

Clot in transit, defined as a mobile right heart thrombus, is a rare but life-threatening manifestation of venous thromboembolism. Its presence in acute pulmonary embolism is associated with high mortality and hemodynamic instability. Diagnosis relies primarily on echocardiography, with adjunctive roles for computed tomography and cardiac magnetic resonance. Management remains challenging due to the absence of randomized trials. Treatment options include anticoagulation alone, systemic thrombolysis, surgical embolectomy, and catheter-based interventions, with outcomes favoring active reperfusion in unstable patients. Multidisciplinary decision-making is essential, and ongoing research aims to clarify optimal strategies to improve survival in this high-risk population.

PMID:
42977386
Bibliographic data and abstract were imported from PubMed on 04 Nov 2026.

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