Keratometric variability after infant cataract surgery: 10-year outcomes from the Infant Aphakia Treatment Study.

Authors

Sheharbano Jafry, Arthur Brant, Scott Lambert

Published in

Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus. Pages 105348. Nov 03, 2026. Epub Nov 03, 2026.

Abstract

To evaluate 10-year changes in corneal curvature and keratometric variability in children with unilateral congenital cataract.
Keratometry data were analyzed from 114 children enrolled in the Infant Aphakia Treatment Study, a multicenter randomized trial of infants treated with either primary intraocular lens implantation or aphakic contact lens correction. Measurements from pseudophakic, aphakic, and fellow eyes were obtained at surgery and at ages 1, 5, and 10 years. Mean keratometry and variance were compared across groups using t tests and F tests.
All eyes showed progressive corneal flattening over time. Mean keratometry did not differ significantly between cataractous and fellow eyes at later time points; however, cataractous eyes demonstrated significantly greater keratometric variability than fellow eyes at ages 1, 5, and 10 years.
Although corneal flattening occurs after congenital cataract surgery, operated eyes show substantial long-term variability in corneal curvature. These findings may affect intraocular lens power prediction and support individualized refractive planning in pediatric cataract patients.

PMID:
42977246
Bibliographic data and abstract were imported from PubMed on 04 Nov 2026.

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