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[Efficacy and safety of "Preserving Ejaculation Function Method" blue laser prostate vaporization for benign prostatic hyperplasia].

Created on 12 Nov 2026

Authors

Quan DU, Kaixuan Zhang, Lin Yang, Dalin He, Yongwei Zhao, Guangwei Zhang, Zhen Tong, Ligang Zhang, Zhihui Zou

Published in

Zhonghua nan ke xue = National journal of andrology. Volume 32. Issue 9. Pages 794-799.

Abstract

Objective The aim of this study is to explore the efficacy and safety of the "sperm preservation method" blue laser prostate vaporization (BVP) in the treatment of benign prostatic hyperplasia (BPH). Methods A prospective study was conducted on the clinical data of 70 patients who underwent BVP under the "sperm preservation method" at 6 medical centers from September 2024 to November 2024. The IPSS, quality of life (QOL) scores, maximum urine flow rate (Qmax), residual urine volume (PVR), IIEF-5, male sexual health questionnaire-ejaculatory dysfunction function score, male sexual health questionnaire-ejaculatory dysfunction distress score, and other related complications were compared between the patients before surgery and at 3 and 6 months after surgery. Results A total of 70 patients were finally followed up completely. All patients successfully completed the surgery. The operation time was (20.41±4.30) minutes. Laser energy consumption was (229.7±110.5) kJ. The declining volume of hemoglobin and blood sodium was 5.25(3.07, 7.35) g/L and 4.76(2.55, 6.83) mmol/L, respectively. The postoperative bladder irrigation time was (18.90±4.3) hours. The postoperative urinary catheter retention time was 59.6 (56.0, 76.7) hours. And the length of hospital stay was 3(2, 4) days. The patients'IPSS at 6 months postoperatively decreased from (23.30±6.57) points preoperatively to (5.03±2.11) points, QOL scores decreased from (4.77±0.71) points preoperatively to (4.77±0.71) points, and Qmax increased from (8.90±3.11) mL/s preoperatively to (19.67±1.27) mL/s, representing a significant improvement compared to preoperative levels (P<0.01). PVR was 0 (0, 71.5) mL preoperatively, and 0 (0, 0) mL at both 3 and 6 months postoperatively (P<0.01). Sixty-three patients had sexual activity 6 months after surgery, and there was no statistically significant difference in IIEF-5 scores, male sexual health questionnaire-ejaculatory dysfunction function score, and male sexual health questionnaire-ejaculatory dysfunction distress score before and after surgery (P>0.05). Among the 63 patients with sexual activity at 6 months after surgery, only 4 cases (6.35%) had retrograde ejaculation. And among the 59 patients with normal ejaculation, 35 cases had no difference in ejaculation volume compared to before surgery, and 24 cases had a decrease in ejaculation volume compared to before surgery. No severe complications of Clavien grade III or above were found in all patients after surgery. The protection rate of ejaculatory function for patients with normal sexual function reached 93.65%. Conclusion The "ejaculatory function preservation method" BVP resulted in significant improvement in patients' urinary symptoms six months after surgery and provided effective protection of their ejaculatory function.

PMID:
43017714
Bibliographic data and abstract were imported from PubMed on 12 Nov 2026.

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