Latest Research Publications - Life Science Network

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Created 21 Oct 2026

A tunable immune-evasion function of Zika virus NS5 governs viral fitness and pathogenesis.

by Yu Zhang, Yaqing Zhang, Chengyu Liu, Wenlin Ren, Yu Zhao, Chenhao Li, Yongqi Guo, Leyi Bai, Peigang Wang, Jing An, Jun Liu, Qiang Ding — Proceedings of the National Academy of Sciences of the United States of America. Volume 123(43): e2630605123. Oct 27, 2026.
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Created 21 Oct 2026

Methanogenic archaea Methanobrevibacter smithii and Methanosphaera stadtmanae promote mucosal homeostasis and protect from colitis.

by Emily E Byrd, Benjamin W Harris, Hongpan Zhang, W Elise Warren, Sree H Kolli, Audrey M Putelo, Mitchell T McGinty, Michael D Solga, Melanie R Rutkowski, Melissa M Kendall — Proceedings of the National Academy of Sciences of the United States of America. Volume 123(43): e2610622123. Oct 27, 2026.
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Created 21 Oct 2026

Molecular basis for discrimination of cGAMP linkage isomers by a c-di-GMP-II riboswitch variant.

by Xiaochen Xu, Wang Cheng, Huiqin You, Zejia Hu, Xinyue Bao, Hongcheng Li, Jinzhu Zhang, Dinshaw J Patel, Aiming Ren — Proceedings of the National Academy of Sciences of the United States of America. Volume 123(43): e2621568123. Oct 27, 2026.
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Created 21 Oct 2026

PSF3 recruits Polθ to stalled replication forks to promote DNA repair.

by Umeshkumar Vekariya, Benjamin Lee Prather, Roland L Dunbrack, Rongsheng E Wang, Tomasz Skorski — Proceedings of the National Academy of Sciences of the United States of America. Volume 123(43): e2613699123. Oct 27, 2026.
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Created 21 Oct 2026

Bridging spatial scales in respiratory viral infection.

by Ulrik Hvid, Bjarke Frost Nielsen, Kim Sneppen — Proceedings of the National Academy of Sciences of the United States of America. Volume 123(43): e2614436123. Oct 27, 2026.
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Created 21 Oct 2026

Structure of bovine viral diarrhea virus E2 glycoprotein in complex with CD46 reveals the molecular basis of virus-receptor recognition.

by Yanping Duan, Sheng Lin, Fei Wang, Yu You, Zimin Chen, Liyan Guo, Wenjie Gong, Lianjing Liang, Shiyuan Tang, Hai-Fang Yu, Yarong He, Bin He, Zhi Wan, Yu Cao, Fanli Yang, Guangwen Lu — Proceedings of the National Academy of Sciences of the United States of America. Volume 123(43): e2620643123. Oct 27, 2026.
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Created 21 Oct 2026

Connexins are essential for the contribution of latent progenitors to healing after spinal cord injury.

by María Victoria Falco, Gabriela Fabbiani, Daniel Prieto, Mateo Vidal, Milagros Benítez, María Inés Rehermann, María Constanza Silvera, Renata Simeone, Federico F Trigo, Raúl E Russo — Proceedings of the National Academy of Sciences of the United States of America. Volume 123(43): e2605647123. Oct 27, 2026.
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Created 21 Oct 2026

CX3CL1 (fractalkine)-CX3CR1 interface drives CD8⁺ T cell-induced neurodegeneration in human brain organoids.

by Woo Sub Yang, Min Sun Shin, Mu Seog Choe, Ferdi Ridvan Kiral, Jumee Kim, Hong-Jai Park, Mario Felix, Lais Osmani, In-Hyun Park, Insoo Kang — Proceedings of the National Academy of Sciences of the United States of America. Volume 123(43): e2605209123. Oct 27, 2026.
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Created 21 Oct 2026

PLD1-driven oncogenic secretion creates a therapeutic vulnerability in chromosome 3q-amplified NSCLC.

by Xiaochao Tan, Shike Wang, Sieun Lee, Guan-Yu Xiao, Derrick L Cardin, Dakai Zhang, Yuting Xu, Chao Wu, Biyao Zhou, William K Russell, Guangwei Du — Proceedings of the National Academy of Sciences of the United States of America. Volume 123(43): e2532484123. Oct 27, 2026.
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Created 21 Oct 2026

Mediator-associated proteins and the small RNA-guided Polycomb repressive complex enhance cryptic transcription for transposon exclusion.

by Zhihao Zhai, Haoyu He, Tomoko Noto, Mingmei Liucong, Jialuo Li, Julie Saksouk, Yike Liu, Xue Wang, Yujie Liu, Kazufumi Mochizuki, Miao Tian — Proceedings of the National Academy of Sciences of the United States of America. Volume 123(43): e2606005123. Oct 27, 2026.
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