Latest Research Publications - Life Science Network

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Created 11 Nov 2026

A trefoil knot mimic and multiple pore states define the mechanism of a split-shell Tc toxin.

by Oleg Sitsel, Raphael Bader, Peter Njenga Ng'ang'a, Patrick Günther, Leonie Kerkmann, Lara Kroczek, Alexander Belyy, Debora Obergfäll, Petra Janning, Stefan Raunser — Proceedings of the National Academy of Sciences of the United States of America. Volume 123(46): e2626865123. Nov 17, 2026.
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Created 11 Nov 2026

The highly heat-inducible HspA6 and the thermolabile DnaJB5 are potent regulators of heat shock transcription factor 1 activity.

by Moritz Koch, Yuantao Huo, Szymon W Kmiecik, Stefan Lenz, Matthias P Mayer — Proceedings of the National Academy of Sciences of the United States of America. Volume 123(46): e2623767123. Nov 17, 2026.
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Created 11 Nov 2026

Host infection selects for sRNA variants that drive bacterial social cheating.

by Quentin Dubois, Typhaine Brual, Marcel Sprenger, Véronique Utzinger, Romain Mercier, Jérémy Cigna, Agnès Rodrigue, Kai Papenfort, Laetitia Attaiech, Erwan Gueguen — Proceedings of the National Academy of Sciences of the United States of America. Volume 123(46): e2621458123. Nov 17, 2026.
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Created 11 Nov 2026

Disruption of the NTCP-EGFR receptor complex as a strategy for selective inhibition of hepatitis B and D virus entry.

by Atsuto Kusunoki, Kaho Shionoya, Frank Stappenbeck, Takeshi Morita, Hirofumi Ohashi, Noritaka Kagaya, Makoto Nagano, Junki Mifune, Ryo Morishita, Feng Wang, Tetsuya Toyoda, Norimichi Nomura, Kazuo Shin-Ya, Kazuhiko Katayama, Farhad Parhami, Koichi Watashi — Proceedings of the National Academy of Sciences of the United States of America. Volume 123(46): e2603986123. Nov 17, 2026.
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Created 11 Nov 2026

IFITM1-mediated restriction of henipavirus entry is associated with ephrinB2 reorganization and confinement in membrane nanodomains.

by Yuhang Luo, Jingjing Wang, Jiake Li, Qian Wang, Jacqueline Sung, Vicky Kliemke, Mengyu Zhang, Chen Liang, Qian Liu — Proceedings of the National Academy of Sciences of the United States of America. Volume 123(46): e2615997123. Nov 17, 2026.
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Created 11 Nov 2026

N-terminal integrity governs heptamer assembly and maturation in a mosquito innexin hemichannel.

by Shota Kawaguchi, Takahito Nakano, Hidemi Hirano, Masakatsu Watanabe, Shota Suzuki, Kouki Nishikawa, Yoshinori Fujiyoshi, Atsunori Oshima — Proceedings of the National Academy of Sciences of the United States of America. Volume 123(46): e2627957123. Nov 17, 2026.
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Created 11 Nov 2026

Acute degradation of Pumilio proteins reveals a biphasic posttranscriptional regulatory hierarchy in embryonic stem cell fate decision.

by Yuedong Huang, Wenxue Li, Hanna Richman, Yansheng Liu, Haifan Lin — Proceedings of the National Academy of Sciences of the United States of America. Volume 123(46): e2619145123. Nov 17, 2026.
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Created 11 Nov 2026

Spatial transcriptomics reveals organizational properties of the mouse spinal cord and alterations in neuropathic pain.

by Qimeng Wang, Yunfei Hu, Yuling Zhu, Gautham Chelliah, Jing Peng, Emmanuella Osei-Asante, Melissa Sobanko, Brianna Sanchez, David D Ginty, Xin Maizie Zhou, Shan Meltzer — Proceedings of the National Academy of Sciences of the United States of America. Volume 123(46): e2623177123. Nov 17, 2026.
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Created 11 Nov 2026

Homeostatic control of stem cell activity during intestinal regeneration.

by Shichao Yang, Jiahui Huang, Changsheng Luo, Guofan Peng, Ke-Wei Zheng, Kang Han, Jun Zhou — Proceedings of the National Academy of Sciences of the United States of America. Volume 123(46): e2618514123. Nov 17, 2026.
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Created 11 Nov 2026

PhagoCyt enables isolation of Salmonella-containing phagosomes and mapping of host and bacteria remodelling of the intracellular niche.

by Ritika Chatterjee, José Luis Marin-Rubio, Francesca Romana Cianfanelli, Andrew Michael Frey, Benjamin Bernard Armando Raymond, Abeer Dannoura, Camila Valenzuela, Meihan Meng, Tiaan Heunis, Mengchun Li, Frances Sidgwick, Jost Enninga, Andrew Filby, Matthias Trost — PLoS biology. Volume 24(11): e3004073. Nov 10, 2026.
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