Preprints

Created 24 Jul 2026

MYC/MIZ1 suppression of lysosomal protein degradation drives immune evasion in pancreatic ductal adenocarcinoma

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Created 25 Jul 2026

Bioengineering of a Chimeric Metarhizium anisopliae cPr1A Protease with Enhanced Binding and Enzyme Activity Through C-terminal Fusion of Bombyx mori Chitin-Binding Domain

by Maurya, N., Saini, G. K.

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Created 16 Jul 2026

Prediction-Guided Design of a More Developable FGF21 Construct

by Bozkurt, C., Nathanail, E., Goteti, A.

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Created 17 Jul 2026

CurateMake: an auditable workflow for multi-source ITS reference database harmonisation and phylogenetic validation

by Gardette, A., Belda, E., Prifti, E., Zucker, J.-D.

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Created 21 Jul 2026

A Lipocalin and a Hedgehog-related protein are partners in the C. elegans pre-cuticle apical extracellular matrix

by Serra, N. D., Chen, J., Birnbaum, S. K., Aviles, S. G., Sundaram, M. V.

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Created 11 Jul 2026

Integrative multiomics profiling of cortical brain organoids reveals a druggable alternative splicing program in schizophrenia

by Akkouh, I. A., Osete, J. R., Szabo, A., Steen, V., Torsvik, A., Molden, E., Parker, N., Koch, E., Ziller, M., Andreassen, O., O'Connell, K., Djurovic, S.

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Created 24 Jul 2026

DROSOPHILA PRICKLE MUTANTS DISPLAY COMORBID NEUROLOGICAL PHENOTYPES AND PROVIDE A GENETIC LINK BETWEEN EPILEPSY AND AUTISM SPECTRUM DISORDER

by Nukala, K. M., Williquett, B., Lilienthal, A. J., Thompson, D. M., Massingham, J. N., Lye, S. H., Yu, A., Lear, B. C., Neely, G. G., Chtarbanova, S., Manak, J. R.

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Created 24 Jul 2026

A highly penetrant LMNA R541C variant associated with dilated cardiomyopathy leads to dysregulation in metabolism and proliferation pathways in stem cell-derived cardiomyocytes

by Keller, T. E., Koehring, C., Higgins, B. R., Yang, J., Siddiqui, F. A., Farsaei, F., Kim, K., McDonald, T. V.

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Created 21 Jul 2026

Under pressure: Evolutionary trade-offs shape the single visual opsin of deep-sea octopods

by De Vivo, G., Ma, M., Forni, G., Luchetti, A., Crocetta, F., Lienard, M. A., D'Aniello, S.

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Created 15 Jul 2026

MTB-LysB1: A Novel Endolysin Against Multidrug-resistant Mycobacterium tuberculosis

by Arora, R., Kandasamy, E., Rani, J., Singh, A. K., Bajpai, U.

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