Latest Research Preprints - Life Science Network

Preprints

The Preprints module of the Life Science Network is an archive of pre-publication manuscripts. You can use it to upload your own preprints and give your research more exposure. Preprints may also be automatically imported from other databases.

You can upload a preprint here

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This list contains preprints from the last 30 days only. Use the search function to access older preprints.

The default sorting of preprints in this list is by the date when the preprint was uploaded or imported to our database (shown on top). Publication date is indicated below the title.

Created 07 Aug 2026

MaskTalk: cell-identity-gated spatial lag for target-aware cell-cell communication inference in high-resolution spatial transcriptomics

by Jia, P., Chu, L., Ren, Z., Cui, H., Shao, B.
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Created 07 Aug 2026

Evaluating the ability of spatial transcriptomics foundation models to learn multi-scale spatial variation

by Handa, D., Martin-Linares, C., Stein-O'Brien, G., Ling, J., Chitra, U.
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Created 06 Aug 2026

Brain circuitry behavioral control emerging from complexity of nested recurrent loops extending into the body

by Szeier, S., Jorntell, H.
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Created 24 Jul 2026

Programming protein shape as an explicit design layer via CAD blueprint-guided diffusion

by Qi, Y., Zhang, G., Yserentant, K., Lee, S., Lyubimov, A., Ibrahim, K., Cimicata, G., Fraser, J. S., Huang, B., Kortemme, T.
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Created 31 Jul 2026

Resolving Immune Lineage and Cell-State Heterogeneity in Human PBMCs via Mass Spectrometry-Based Single-Cell Proteomics

by O'Connor, S. A., Gletten, R. B., Sharma, R., Jensen, Z. N., Lovell, B., Garcia-Mansfield, K., Ghoda, L. Y., Zhang, B., Frankhouser, D. E., Rockne, R. C., Trent, J. M., Marcucci, G., Pirrotte, P.
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Created 18 Jul 2026

Large-scale dimensional behavioral profiling dissociates fear memory from locomotor confounds in mice: The necessity of baseline-normalized metrics
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Created 22 Jul 2026

HDAC3 inhibitor RGFP966 acts on the NF-kB pathway and enhances memory persistence in a biphasic manner

by Robles, A. D., D'hers, S., Feld, M., Romano, A.
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Created 10 Aug 2026

FOCUS: end-to-end preprocessing, alignment and resolution-matched integration of spatial multi-omics data

by Venturelli, L., Jacobs, J., Sifrim, A.
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Created 04 Aug 2026

Probing Mechanisms of Allosteric Regulation in AAA+ ATPases for Microtubule Severing and Protein Disaggregation

by Irshad, M., Walpalage, K., Zhang, Z., Gillen, M. S., Dima, R. I., Stan, G.
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Created 28 Jul 2026

A Portable Fluorescence Platform for Decentralized One-Health mcr-1 Monitoring

by Vargas-Reyes, M., Alcantara, R., Herrera, C., Townsend, M., Flores-Jimenes, K., Raymundo, C., Milon, P.
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