Preprints

Created 16 Aug 2026

LEN-Seek: Fast and scalable ligand binding-site similarity search in the latent space of an SE(3)-invariant graph VAE

by Yeo, K., Kim, D., Sim, J., Lee, J.

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Created 16 Aug 2026

Activity-based chemical proteomics uncovers unexpected covalent targetsof E64d and reveals a role for cysteine cathepsins in PLD3 proteostasis.

by Hertwig, M., Kielkowski, P.

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Created 16 Aug 2026

ATP-dependent reorientation on a nucleosome primes INO80 for DNA translocation

by Wu, H., Kaur, U., Li, C., Munoz, E. N., Narlikar, G. J., Cheng, Y.

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Created 16 Aug 2026

Structural basis of K<+>/H<+> antiport in YcgO and its inhibition by unphosphorylated PtsN

by Srivastava, A., Athreya, A., Patidar, Y., Singh, V., Sardesai, A. A., Penmatsa, A.

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Created 16 Aug 2026

Long-read sequencing quantifies synthetic mRNA abundance, integrity and host response in vivo

by McLeod, V. M., Yuen, D., Chen, M. Z., Beckham, S. A., Feeney, O. M., Rossi Herling, B., Yang, Y., Molle, L. M., Kaur, P., Payne, T. J., Fabb, S. A., Pouton, C. W., Porter, C. J. H., Johnston, A. P. R.

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Created 16 Aug 2026

A NON-CANONICAL ROLE FOR NOTCH3 IN BUILDING THE INTESTINAL LYMPHATIC NICHE

by Kurpios, N. A., Huang, L., Sanketi, B., Mantri, M., Chen, Y., Wang, C., Tran, T., De Vlaminck, I.

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Created 16 Aug 2026

Trustworthy in silico labeling via semantic visual interpretability of image-to-image translation

by Ben Nedava, L., Miller, G., Elmalam, N., Viana, M. P., Chen, J., Gaudreault, N., Rafelski, S. M., Zaritsky, A.

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Created 16 Aug 2026

High-throughput screening in hiPSC-cardiac models reveals cardiomyocyte-specific cell cycle regulatory mechanisms

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Created 16 Aug 2026

DNA gyrase in live bacteria forms liquid condensates through weak multivalent bonding of excess GyrB

by Syeda, A., Hollnds, K., Frame, L., Shepherd, J., Payne-Dwyer, A. C., Goffee, E., Burton, N., Basu, A., Noy, A., Maxwell, T., Leake, M. C.

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Created 16 Aug 2026

A multi-omics view of wax synthesis in the wild cochineal bug, Dactylopius opuntiae

by Dessert, J., Marcotte, E. M., Ochman, H.

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