Preprints

Created 22 Jun 2026

Molecular mechanisms underlying amyloid lowering by aducanumab: differential and comparative effects of sex and IgG reveal the post-treatment disease brain

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Created 22 Jun 2026

Antibody-Antigen Affinity Prediction with Chain-Aware Protein Language Modeling

by Singh, H., Malhotra, A., Srivastava, S. P., SINGH, R. K., Gorantla, R.

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Created 20 Jun 2026

Intersegmental transfers drive target search in an RNA-targeting CRISPR system

by Kimchi, O., Larsen, B. B., Gibson, E., te Velthuis, A. J. W., Myhrvold, C.

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Created 20 Jun 2026

Geometric Deep Learning Reveals Ligandable and Cryptic RNA Binding Small Molecule Pockets (SMARTPocket)

by Thakare, R. H., Taghavi, A., Wang, J., Childs-Disney, J. L., Li, C., Disney, M. D., Li, Y.

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Created 20 Jun 2026

The road to nowhere: geolocation-by-genotype traces large-scale yellow-browed warbler vagrancy to central Siberia

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Created 20 Jun 2026

OmniPath Metabo: chemical structures, interactions and mechanisms to study the metabolome

by Schaul, J., Bai, Y., Franken, J., Lawrence, T., Palacio-Escat, N., Bottazzi, D., Carreno, E., Daley, M., Gul, L., Sahin, A., Mananes, D., Bohar, B., Dugourd, A., Korcsmaros, T., Turei, D., Schmidt, C., Saez-Rodriguez, J.

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Created 20 Jun 2026

Perturbation Curve models continuous transcriptional response trajectories and improves prediction of genetic modulations

by Zhong, Y., wang, l., Yang, G., Yu, L., Qi, X., Jiang, H.

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Created 22 Jun 2026

Defining reversible binding rates in 1D systems dependent on diffusion, density, and excluded volume

by Sang, M., Johnson, M. E.

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Created 22 Jun 2026

SAbDab2: The structural antibody database in the age of machine learning

by Capel, H. L., Vavourakis, O., Williams, B. H., Taylor, C. R., Deane, C. M.

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Created 22 Jun 2026

Combination epigenetic-targeted therapy increases the immunogenicity of poorly immunogenic sarcomas

by Recho, A., Gatla, H. R., Resch, E. E., Phillips, M. J., Glavaris, S., Doucet, M., Looi, A. N. M., Barbato, M. I., Llosa, N. J., Koldobskiy, M. A., Ladle, B. H.

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