Preprints

Created 21 Oct 2026

ALLCAPS: a scalable and accurate deep-learning method for in silico pneumococcal serotyping

by Tajmirriahi, A., Mateeva, T., Russell, M. J., Lorenz, O., Kim, S. J., Lo, S. W., Bentley, S. D., Lees, J. A., Horsfield, S. T.

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Created 12 Oct 2026

EARLY-LIFE STRESS INDUCES SEXUALLY DIMORPHIC BRAIN AGING VIA MESOLIMBIC ALTERATIONS AND FRONTO-STRIATAL DYSFUNCTION

by Souza, A. C., Tibirica, I. C. G., Mariano, V. S., Grigoletti-Lima, G. B., Gontijo, J. A. R., BOER, P. A.

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Created 28 Oct 2026

ESX-1 substrates ESAT-6 and CFP-10 limit cGAS-STING activation via DNA and Zn2+ restriction

by Xu, L., Huang, J., Pan, D., Wu, C., Chang, T., Lu, J., Zhao, X., Wang, H., Li, S., Zhu, L., Sun, Y., Wang, Y., Shen, X.

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Created 23 Oct 2026

Optimizing Cognitive Phenotyping for Genetic Discovery in Alzheimer's Disease: A Simulation-Based Evaluation of Mini-Mental State Examination-Based Decline Measures

by Shi, R., Feingold, E., Kamboh, I. M., Fan, K.-H.

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Created 23 Oct 2026

WRN deficiency generates oncogenic rearrangements at TA-rich tandem repeats

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Created 15 Oct 2026

Preoperative thymic output and T cell repertoire diversity are associated with recurrence after nephrectomy for localized renal cell carcinoma

by Grand, C. E., Iisager, L., Attermann, A. K., Nordentoft, I., Zanini, L., Juul, R. I., Keller, A. K., Thorlund, M. G., Eisum, A.-S. V., Nielsen, T. K., Jespersen, J., Fristrup, N., Dyrskjoet, L., Birkbak, N. J., Lyskjaer, I.

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Created 24 Oct 2026

CAI-Vax: Computational Design of Personalized mRNA Cancer Vaccine Constructs After Antigen Selection

by Cai, J., Chen, Y., Sun, Y., He, I., Yuan, L., Liu, E., Lee, W. H.-M., Lu, Z.

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Created 21 Oct 2026

geoGraph: Connectivity modelling across geographic space with hexagonal discrete global grids

by Jud, D. C., Carter, E. J., Pozzi, A. V., Pelanek, O., Fatima, A., Colucci, M., Padilla-Iglesias, C., Leonardi, M., Chang, S., Gunasekaram, C., Vinicius, L., Migliano, A. B., Jombart, T., Manica, A.

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Created 12 Oct 2026

Coronavirus nucleocapsid proteins differentially antagonize RIG-I-like receptor signaling to shape pathogenicity

by Rui, Y., Wang, Y., Chen, S., Cao, Y., Hu, Y., Shen, S., Ding, Q., Su, J., Yu, X.-F.

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Created 16 Oct 2026

Repeated Neuromuscular Electrical Stimulation Protocol Disrupts Muscle-to-Brain Signaling in Rats

by Wirtz, J., Wang, Y., Chaney, R., Wirtz, L., Drezet, Q., Papaxanthis, C., Quirie, A., Meloux, A., Lemaire, S., Cefis, M., Tessier, A., Garnier, P.

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