About
Summary
My research interests include genetics and development, cell and molecular biology, genome editing and advanced cell culture; my latest project is to develop novel platforms to assess the safety profile of gene therapy effectors. I have an extensive hands-on experience in molecular and cell biology, with CRISPR/Cas cell engineering technologies and within the field of RNA modifications.
Positions
Associate Director Dec 2025 -
Senior Reserach Scientist Sep 2023 - Nov 2025
Postdoc Sep 2020 - Sep 2022
Postdoc Apr 2017 - Mar 2020
Biology and Biological Engineering, Chalmers University of Technology
My project was to study how to deliver therapeutic RNA sequences into a cellular model for Amyotrophic Lateral Sclerosis (ALS), to gain insight on its onset and spreading, thus preventing or disassembling cytotoxic protein aggregates, commonly found in several neurodegenerative diseases.
Postdoc Mar 2016 -
Developmental Cell Dynamics Lab, Chalmers University of Technology
The Developmental Cell Dynamics Lab focuses on understanding preimplantation mammalian development by combining advanced live-cell imaging and genetic approaches with computer-based mathematical modeling and simulations of cell dynamics, combined with high-throughput genomics, transcriptomics and proteomics data analysis. During this postdoctoral training, I will expand both my conceptual and technical skills, paying special emphasis to the dynamics of early mammalian embryo development.
PhD student Oct 2012 - Feb 2016
PhD Degree, with a concentration in Genetics and Molecular Biology – Sapienza University, under the supervision of Prof. P. Dimitri
PhD thesis title : “Effects of BCNT domain-containing genes depletion on global expression in Drosophila melanogaster and Danio rerio.”
Education
Sapienza University of Rome, Italy 2012 - 2016
Field of study: Genetics and molecular biology
Degree: PhD
Skills
Drosophila melanogaster and Danio rerio Genetics, Experimental design, Preparation of solutions, Isolation and purification of nucleic acids and proteins, PCR, RT-PCR, qPCR, gene cloning, Gel electrophoresis, Spectrophotometry, Cells culture, RNAi silencing technology, Morpholino silencing technology, In Situ Hybridization, Immunohistochemistry, Optical and fluorescence microscopy, Microdissection, Use of microtome to prepare tissue sections, Deep ICT knowledge as systems analyst (Windows and Linux), Use of several imaging and genomics softwares.
Professional interests
Drosophila melanogaster, Danio rerio, genetics, molecular biology, cell culture, cell cycle, chromosome dynamics, human disease modelling
Languages
Italian, English, Swedish, French, Spanish
CV
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