Latest Research Publications - Life Science Network

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Created 12 Nov 2026

Discovery of INCB161734: A Selective Inhibitor of the KRAS G12D Mutant.

by Alexander Sokolsky, Haolin Yin, Qinda Ye, Peter Carlsen, Chunyin Law, Matthew S McCammant, Rocco Policarpo, Padmaja Polam, Le Zhao, Fenglei Zhang, Gencheng Li, Bin Hu, Wenyu Zhu, Gia Hoang, Robert Susick, Zhenwu Li, Pei Gan, Artem Shvartsbart, Jeremy J Roach, Chao Qi, Sean Bowen, Chengtsung Lai, Abdellah Allali-Hassani, Keith Kennedy, Leslie B Epling, Alexandra Gallion, Kerri Kurzeja-Lipinski, Karen Gallagher, Valerie Roman, Matthew R Farren, Weixi Kong, Guofeng Zhang, Jason Boer, Marc C Deller, Hui Wang, Maryanne Covington, Jennifer J Harris, Sunkyu Kim, Dashyant Dhanak, Wenqing Yao, Xiaozhao Wang — Journal of medicinal chemistry. Volume 69(21): 25112-25127. Nov 12, 2026.
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Created 12 Nov 2026

Comparative analysis of respiratory infection and clinical outcomes in Saudi hematology: malignant versus non-malignant cohorts.

by Zinab O Doha, Aiah M Khateb, Ahmed S Barefah, Osman Radhwi, Ali Algiraigri, Lina Alhejaili, Sadeem Alhelali, Hadeel Alhazmi, Khloud Almgthwi, Esam I Azhar — Frontiers in cellular and infection microbiology. Volume 16: 1916017. Epub Oct 28, 2026.
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Created 12 Nov 2026

Twelve novel Italian cases of hypophosphatasia: challenging cases with an extremely variable phenotype.

by Giulia Casamassima, Tommaso Biagini, Flavia Pugliese, Anna Maria Grieco, Francesco Petrizzelli, Tommaso Mazza, Mauro Celli, Emanuela Scarano, Federica Tamburrino, Luciano Colangelo, Cristina Eller-Vainicher, Anda Mihaela Naciu, Gaia Tabacco, Giovanni Rossini, Francesca Pigliaru, Andrea Palermo, Silvia Morlino, Bartolomeo Augello, Antonio Petracca, Marco Castori, Alfredo Scillitani, Vito Guarnieri — Frontiers in endocrinology. Volume 17: 1966666. Epub Oct 28, 2026.
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Created 12 Nov 2026

Immune-mediated comorbidities in multiple sclerosis: a scoping review.

by Austin Daniel Solak, Patricia Mariana Riccio, Da Hee Seo, Samin Ayromlou, Azhar Mohammed Alanazi, Juan Manuel Racosta — Frontiers in immunology. Volume 17: 1911169. Epub Oct 28, 2026.
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Created 12 Nov 2026

Geographic concordance of cataract and glaucoma burden and associated country-level exposures across 204 countries and territories.

by Qiao Chen, Xueying Yang, Liang Li, Changzheng Chen — Frontiers in public health. Volume 14: 1901226. Epub Oct 28, 2026.
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Created 12 Nov 2026

High efficacy and tolerability of daratumumab-based regimens in first-line treatment of patients with immunoglobulin light-chain amyloidosis: a real-world evidence analysis.

by Yajuan Cui, Yunya Luo, Ji Li, Lingli Yuan, Zhihua Wang, Hongling Peng, Ruijuan Li — Frontiers in immunology. Volume 17: 1960805. Epub Oct 28, 2026.
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Created 12 Nov 2026

Bone metastases identify a high-risk subgroup in metastatic neuroendocrine tumors with particular relevance in NETs of unknown primary.

by Annie Mathew, Anna Kyewski, Pia Hauptmeier, David Kersting, Benedikt M Schaarschmidt, Dagmar Fuhrer, Harald Lahner — Frontiers in endocrinology. Volume 17: 1906789. Epub Oct 28, 2026.
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Created 12 Nov 2026

Persistence and remission of depressive and generalized anxiety symptoms among adolescent mothers in Mwanza, Tanzania: a longitudinal observational study embedded within a non-pharmacological intervention cohort.

by Matiko Mwita, Deborah Dewey, Eveline T Konje, Scott Patten — Frontiers in global women's health. Volume 7: 1814117. Epub Oct 28, 2026.
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Created 12 Nov 2026

Beyond functional disability: longitudinal joint trajectories of muscle strength and walking speed and their association with new-onset diabetes risk among older adults without ADL impairment.

by Xiangyang Chen, Xuan Wu, Sizhe Feng — Frontiers in endocrinology. Volume 17: 1935223. Epub Oct 28, 2026.
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Created 12 Nov 2026

Neurologic outcomes following intubation with non-depolarizing vs. depolarizing paralytics in status epilepticus: a target trial emulation.

by Patrick King, Juan Garcia-Mendez, Aysun Tekin, Diksha Gowda, Anes Joguncic, Amos Lal — Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures). Volume 12(4): 673-685. Epub Oct 30, 2026.
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