Preprints

Created 30 Sep 2026

MIMOSA: Guiding De Novo Antibody Design with Natural Interaction Fingerprints

by Abanades, B., Roncoli, A., Bhagawati, M., Kessel, P., Imhof-Jung, S., Doerr, D., Schilz, J., Vasilaki, S., Seeger, F., Bonvin, A. M. J. J., Bonneau, R., Gligorijevic, V., Vangone, A.

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Created 29 Sep 2026

Glutamine and GLS1 are key metabolic checkpoints that Limit T cell Infiltration and Function in HNSCC

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Created 30 Sep 2026

Mapping a genome-scale in vivo knockout screen to a mechanistic network model identifies VAV2, RASA1, and LEPR as regulators of cardiomyocyte hypertrophy

by Watkins, L. D., Saucerman, J. J.

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Created 27 Sep 2026

Parents' neural dynamics in response to their children's speech

by Elmlinger, S., Rosenberg, E., Jaffe-Dax, S., Nencheva, M. L., Lee, C., Kosie, J. E., Lew-Williams, C.

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Created 26 Sep 2026

Copy number signatures in targeted gene panels associate with patient outcomes in routine clinical data

by Netz, E., Moris, C., Hasanovic, A., Möbs, M., Schlomm, T., Frost, N., Mohr, R., Stintzing, S., Braicu, E., Sehouli, J., Rieke, D. T., Benary, M., Horst, D., Dubois, F.

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Created 28 Sep 2026

Variant-Specific Rewiring of Lysosomal Positioning by STARD9 Produces Opposite Cholesterol Trafficking Outcomes

by Dianatpour, M., Banerjee, D., Kim, H., Moon, J., Zhu, R., Zhou, H., Neogi, A., Rugira, T., Mane, S., Adeniran, A., Paliuqi, B., Lee, H.-J., Ohno-Machado, L., Mani, A.

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Created 29 Sep 2026

Is shorter faster? The geometry and aerodynamics of crank length in cycling

by Delp, S., Kuhl, E.

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Created 29 Sep 2026

A low-matrix organoid-T cell co-culture platform for functional evaluation of T cell engagers in patient-derived colorectal cancer organoids

by PINNA, C. M. A., Rakhimova, K., Zhang, J., Bills, L., Tee, L., Blanc, C., Millar, D. G., Rottoli, E., Huhn, O., Gaspar, M., Lal, N., Lara, R., Marley, K. A., Cemerski, S., Dovedi, S., Beggs, A. D.

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Created 25 Sep 2026

Negative supercoiling facilitates human TOP3α-mediated decatenation of DNA braids via catenation junction melting

by Saravanan, S., Koetje, A. I., King, G. A., Rueda, D. S., Aragon, L.

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Created 25 Sep 2026

Histotripsy-induced vascular remodeling in the tumor microenvironment enhances local and off-target intratumoral drug delivery

by Queen, H., Song, B., Kim, H., McGinnis, R., Liu, J., Sanogo, A., Buglak, K., Karanam, C., Bontrager, A., Worlikar, T., Xu, Z., Ganguly, A., Cho, C. S.

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