Preprints

Created 04 Aug 2026

Overcoming the accuracy-generalization tradeoff in docking and scoring for prospective virtual screening

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Created 09 Aug 2026

Denisovan leg bones from Taiwan reveal large body size

by Kaifu, Y., Chang, C.-H., Tarusawa, Y., Sawafuji, R., Yonemoto, S., Shimamura, S., Takai, M., Kono, R. T., Sun, C.-H., Tsai, C.-H., Yoneda, M., Tsutaya, T.

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Created 27 Jul 2026

Multi-channel high-density single-molecule localization

by Sha, H., Muller, L.-R., Castillo Duque de Estrada, N. M., Mathieu, M., Jaques, A., Marin, Z., Zhang, Y., Macke, J. H., Ries, J.

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Created 05 Aug 2026

Multi-scale modeling of human tissues from spatial transcriptomics with TERRA

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Created 25 Jul 2026

Beyond Expression Prediction: Benchmarking Differential Expression Classification in Single-Cell Perturbation Models

by Sun, J., He, Y., Zhu, O., Chen, Y. T.

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Created 01 Aug 2026

A Structural Antibody Benchmark of AlphaFold3 reveals Hallucinated Epitopes and a Bias for Orderness

by Solanki, A., Maurya, N. S., Ramlakhan, M., Li, R., Chen, W., Wu, Z., Zheng, W. J.

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Created 29 Jul 2026

A geometric-to-neural cascade for cerebral microbleed detection in susceptibility-weighted MRI

by Bogdanov, S., Rudravaram, G., Saunders, A. M., Kim, M. E., LeFevre, J., Charles, J., Jain, S., Schrag, M. S., Landman, B. A.

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Created 22 Jul 2026

Microglia from Friedreich Ataxia patients are intrinsically primed for neuroinflammation

by Tang, Y. M., Lo, R., Thiry, L., Fiorini, M., Farhan, S., Pandolfo, M., Stifani, S.

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Created 04 Aug 2026

From Abandoned Scripts to FAIR Community Pipelines: Rescuing Orphan Bioinformatics Workflows with nf-core - Lessons from Light-Sheet Fluorescence Microscopy

by Schwitalla, C., Kuhn Cuellar, L., Hoertenhuber, M., Grote, N., Woller, T., Lamberti, I., Pavie, B., Kuestner, T., Kyere, F. A., Curtin, I., Stein, J. L., Nahnsen, S.

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Created 09 Aug 2026

De novo design of a protein fold for small-molecule binding through aromatic π stacking

by Ouchida, S. T., Horst, M. T., Gou, X., Bakanas, I., Hatstat, A. K., Schnaider, L., Diolaiti, M. E., Ashworth, A., DeGrado, W. F.

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