Latest Research Preprints - Life Science Network

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This list contains preprints from the last 30 days only. Use the search function to access older preprints.

The default sorting of preprints in this list is by the date when the preprint was uploaded or imported to our database (shown on top). Publication date is indicated below the title.

Created 21 Jul 2026

Astrocyte dysfunction distinguishes monozygotic twin C9orf72 expansion carriers discordant for amyotrophic lateral sclerosis.

by Shaw, A. C., Pasniceanu, I. S., Stevenson, R., Moutin, C., Erdi-Krausz, G., Parker, M. D., Wyles, M., Souza, C. D. S., Higginbottom, A., Castelli, L., Kirby, J., Hautbergue, G. M., Ferraiuolo, L., Livesey, M. R., Cooper-Knock, J., Shaw, P. J.
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Created 05 Aug 2026

pH-dependent anti-TfR1 NANOBODY(R) molecules deliver efficacious oligonucleotide payloads to muscle and CNS tissues
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Created 18 Jul 2026

Primary Hyperparathyroidism Reveals Limited Adipose Remodeling in Human
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Created 10 Aug 2026

Virtual spatial transcriptomics from histopathology enables prognostic and therapeutic response prediction in cancer

by Jiao, S., Yuan, Z., Lu, D., Xu, Y., Dong, Y., Peng, J.
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Created 21 Jul 2026

Tear Proteomics Reveals RAGE and NLRP3 Inflammasome Pathway Activation in Lacrimal Glands of a Sjögren's Disease Mouse Model

by Li, X., Alba, M., Fernandez, D. J., Ramirez, A. V., Abdelhamid, S., Wang, C., Edman, M. C., Whitelegge, J., Hamm-Alvarez, S. F.
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Created 17 Jul 2026

SYNGAP1 haploinsufficiency disrupts early neurodevelopment and accelerates intrinsic neuronal maturation in human patient-derived models

by Waters, M., Teasdale, L., Byars, S., Mattei, C., Roseno, N. E., Ovchinnikov, D., Scheffer, I. E., Pardoe, H. R., Petrou, S., Maljevic, S.
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Created 31 Jul 2026

Spectronaut-nf: A Nextflow Pipeline for Parallel Processing of DIA Data with Spectronaut

by Kotimoole, C. N., Arefian, M., McKay, E. C., Kasaragod, S., Skoraczynski, G., Collins, B. C.
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Created 04 Aug 2026

Activation of the NAD⁺-Sirtuin Axis Protects Against Chronic Doxorubicin-Induced Subclinical Renal Tubular Injury Through Restoration of Mitochondrial Homeostasis and Suppression of Inflammation

by Saito, K., Hosoda, R., Numazawa, R., Tomoki, H., Nojima, I., Saga, Y., Tatekoshi, Y., Sato, T., Abe, K., Kuno, A.
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Created 24 Jul 2026

Human rhinovirus 16 impairs macrophage cytokine secretion by disrupting NF-κB nuclear translocation and intracellular cytokine trafficking

by Fremont-Debaene, Z., Mansuroglu, Z., Puchot, L., Leduc, M., Bonhomme, F., Arimondo, P. B., Niedergang, F., Faure-Dupuy, S.
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Created 17 Jul 2026

Glycogen-Dependent Metabolic Reprogramming Regulates Microglial Activation and Dysfunction in Neurodegenerative Disease

by McAlister, H., Merchant, H., Mitchener, V., Gatto, N., Thackray, M., Blackburn, E., Shackleton, L., Gentry, M. S., Arancibia Carcamo, L., Lloyd, A. F.
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