Latest Research Preprints - Life Science Network

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This list contains preprints from the last 30 days only. Use the search function to access older preprints.

The default sorting of preprints in this list is by the date when the preprint was uploaded or imported to our database (shown on top). Publication date is indicated below the title.

Created 04 Aug 2026

Activation of the NAD⁺-Sirtuin Axis Protects Against Chronic Doxorubicin-Induced Subclinical Renal Tubular Injury Through Restoration of Mitochondrial Homeostasis and Suppression of Inflammation

by Saito, K., Hosoda, R., Numazawa, R., Tomoki, H., Nojima, I., Saga, Y., Tatekoshi, Y., Sato, T., Abe, K., Kuno, A.
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Created 21 Jul 2026

Tear Proteomics Reveals RAGE and NLRP3 Inflammasome Pathway Activation in Lacrimal Glands of a Sjögren's Disease Mouse Model

by Li, X., Alba, M., Fernandez, D. J., Ramirez, A. V., Abdelhamid, S., Wang, C., Edman, M. C., Whitelegge, J., Hamm-Alvarez, S. F.
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Created 17 Jul 2026

SYNGAP1 haploinsufficiency disrupts early neurodevelopment and accelerates intrinsic neuronal maturation in human patient-derived models

by Waters, M., Teasdale, L., Byars, S., Mattei, C., Roseno, N. E., Ovchinnikov, D., Scheffer, I. E., Pardoe, H. R., Petrou, S., Maljevic, S.
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Created 17 Jul 2026

Glycogen-Dependent Metabolic Reprogramming Regulates Microglial Activation and Dysfunction in Neurodegenerative Disease

by McAlister, H., Merchant, H., Mitchener, V., Gatto, N., Thackray, M., Blackburn, E., Shackleton, L., Gentry, M. S., Arancibia Carcamo, L., Lloyd, A. F.
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Created 18 Jul 2026

CasanovoGUI: a cross-platform desktop application for deep learning-based de novo peptide sequencing with Casanovo

by Wen, B., Li, K., Riffle, M., MacCoss, M. J., Bittremieux, W., Noble, W. S.
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Created 18 Jul 2026

Structural tuning of native type V fimbriae shapes mechanical specialization in Porphyromonas gingivalis

by Wang, Z., Uday, A. B., Nelea, V., Reinhardt, D. P., Tieleman, D. P., Bui, K. H., Zeytuni, N.
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Created 31 Jul 2026

Spectronaut-nf: A Nextflow Pipeline for Parallel Processing of DIA Data with Spectronaut

by Kotimoole, C. N., Arefian, M., McKay, E. C., Kasaragod, S., Skoraczynski, G., Collins, B. C.
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Created 22 Jul 2026

GeneAutomate: A Browser-Based, Integer-Indexed Platform for Dual-Gene-List Functional Annotation and Interactive Network Visualization

by Singh, R. P., Kumar, A.
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Created 25 Jul 2026

Deciphering complete archaic introgression sequences in modern human genomes

by Suo, M., Bi, A., Chen, Q., Yu, D., Jiang, L., Liu, A., Yang, Y., Wang, H., Sun, Y., Nie, L., Chen, R., Yang, Q., Wang, X., Wang, H., Shi, Y., Zhang, D., Wu, D., Zhang, G.
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Created 13 Aug 2026

MicroRNAome of Spodoptera frugiperda in Response to SfMNPV Infection

by Gomez Bergna, S. M., Amoros Morales, L. C., Gonzalez Abad, A., Vilches, J., Tongiani, S. E., Salvador, R., Romanowski, V., Pidre, M. L., Ferrelli, M. L.
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